EFFORT (Ecology from Farm to Fork Of microbial drug Resistance and Transmission) will establish a research programme to study the complex ecology of antimicrobial resistance and the complex interactions between bacterial communities, commensals and pathogens in animals, the food chain and the environment which reaches beyond previously conducted (international) research projects. This will be conducted by a combination of epidemiological and ecological studies using newly developed molecular and bio-informatics technologies. This will include an exposure assessment of humans from animal sources. The ecological studies on isolates will be verified by in vitro and in vivo studies. Moreover, real-life intervention studies will be conducted. Focus will be on predicting and limiting the future evolution and exposure to humans of the most clinically important resistance by synthesising different sources of information in our prediction models.
Knowledge production in EFFORT is structured into 8 interrelated scientific WPs and 2 WPs on knowledge translation. These WPs range from the broad scale of metagenomic-based research, to the epidemiology and ecology, and the public health and economic impact of antimicrobial resistance in the food chain.
Further information on the different aspects of the EFFORT project: